| 176050 | P41846 | WBS14_CAEEL | Protein WBSCR14 homolog (MLX interactor) | DISRUPTION PHENOTYPE | RNAi-mediated knockdown reduces lifespan, which is further reduced on daf-2 or glp-1 mutant backgrounds (PubMed:24699255, PubMed:27001890). RNAi-mediated knockdown causes premature onset of polyglutamine-mediated paralysis (PubMed:24699255). RNAi-mediated knockdown increases spore levels of the microsporidian pathogen N.parisii during infection, on an mxl-2 or mdl-1 mutant background (PubMed:27402359). {ECO:0000269|PubMed:24699255, ECO:0000269|PubMed:27001890, ECO:0000269|PubMed:27402359}. |