| 176096 | P34663 | HM23_CAEEL | Homeobox protein ceh-23 | DISRUPTION PHENOTYPE | Viable and display no obvious neuroanatomical, morphological or locomotory abnormalities (PubMed:11493519). Lifespan reduced in an isp-1 or nuo-6 mutant background and extends lifespan in the short-lived gas-1 and mev-1 mutants (PubMed:28560849, PubMed:21713031). Expression of the G protein-coupled receptor sra-11 is normal in AIY neurons at the larval L1 stage, but drastically reduced in adults (PubMed:11493519). RNAi-mediated knockdown reduces lifespan in various mitochondrial mutant backgrounds, including isp-1;ctb-1, or clk-1 (PubMed:21713031). {ECO:0000269|PubMed:11493519, ECO:0000269|PubMed:21713031, ECO:0000269|PubMed:28560849}. |