| 176143 | P34331 | PLK1_CAEEL | Serine/threonine-protein kinase plk-1 (EC 2.7.11.21) (Polo-like kinase 1) | DISRUPTION PHENOTYPE | Impaired protein polarity (PubMed:18316412, PubMed:20823068). Lengthened AB and P1 cell cycle times (PubMed:18316412, PubMed:20823068). RNAi-mediated knockdown causes defects in germline mitosis including cell-cylce arrest and formation of polyploid nuclei (PubMed:22018922). RNAi-mediated knockdown in plk-2 mutant background causes a loss in sun-1 phosphorylation at 'Ser-8' but not at 'Ser-12' (PubMed:22018922). {ECO:0000269|PubMed:18316412, ECO:0000269|PubMed:20823068, ECO:0000269|PubMed:22018922}. |