176179 | P34540 | KINH_CAEEL | Kinesin heavy chain (Uncoordinated protein 116) (Protein unc-116) | DISRUPTION PHENOTYPE | Conditional knockout in PVD neuron results in a complete microtubule polarity reversal in the anterior dendrite (PubMed:30254025). Conditional knockout in motor neuron reduces the number of mitochondria in the axon (PubMed:30254025). RNAi-mediated knockdown results in reduced dendritic branch formation in PVD sensory neurons (PubMed:21205795). RNAi-mediated knockdown results in an altered distribution of recycling and late endosomes (PubMed:22634595). RNAi-mediated knockdown results in defects in nuclear migration in hyp7 hypodermal precursor cells (PubMed:27697906). RNAi-mediated knockdown in a dhc-1 (js319) mutant background results in defective nuclei migrations in larval hypodermal P-cells (PubMed:27697906). {ECO:0000269|PubMed:21205795, ECO:0000269|PubMed:22634595, ECO:0000269|PubMed:27697906, ECO:0000269|PubMed:30254025}. |