Mine Disruption Phenotype

Gene Info

  • Species:Worm (Caenorhabditis elegans)
  • GeneID:176180
  • Symbol:rfp-1
  • Description:E3 ubiquitin-protein ligase bre-1
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Gene ID Entry Entry Name Protein Name Type Information
176180 P34537 BRE1_CAEEL E3 ubiquitin-protein ligase bre-1 (EC 2.3.2.27) (RING finger protein rfp-1) (RING-type E3 ubiquitin transferase bre-1) DISRUPTION PHENOTYPE Worms arrest their development at L1 stage, and show tail abnormalities (PubMed:14732404). RNAi-mediated knockdown on a glp-1 mutant background causes significant overproliferation of germline cells (PubMed:25564623). {ECO:0000269|PubMed:14732404, ECO:0000269|PubMed:25564623}.