Mine Disruption Phenotype

Gene Info

  • Species:Worm (Caenorhabditis elegans)
  • GeneID:176286
  • Symbol:glp-1
  • Description:Protein glp-1
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Gene ID Entry Entry Name Protein Name Type Information
176286 P13508 GLP1_CAEEL Protein glp-1 [Cleaved into: glp-1/Notch intracellular domain] DISRUPTION PHENOTYPE RNAi-mediated knockdown causes an increase in lifespan and a moderate increase in aak-2 phosphorylation (PubMed:24332851). RNAi-mediated knockdown in a rsks-1 mutant background reduces the formation of proximal germ cell tumors (PubMed:22278922). RNAi-mediated knockdown results in abnormally large oocytes (PubMed:19502484). {ECO:0000269|PubMed:19502484, ECO:0000269|PubMed:22278922, ECO:0000269|PubMed:24332851}.