| 176449 | Q22289 | TBX9_CAEEL | T-box transcription factor tbx-9 | DISRUPTION PHENOTYPE | RNAi-mediated knockdown causes about 5% embryonic lethality with 1-10% of hatching larvae displaying posterior morphological defects (PubMed:15892873, PubMed:15102704). Defective intercalation of dorsal hypodermis (PubMed:15102704). Simultaneous RNAi-mediated knockdown of tbx-8 causes at least 48% of embryos to fail to hatch and those that do display severe morphological defects and die as larvae (PubMed:15892873, PubMed:15102704). Simultaneous RNAi-mediated knockdown of tbx-8 abolishes muscle expression of vab-7 (PubMed:15102704). RNAi-mediated knockdown at the larval L1 stage causes a decrease in expression of lin-39 at the larval L3 stage (PubMed:24885717). Knockdown in L1 stage larvae, in a lin-39 mutant background, causes abnormal fusion of vulval precursor cells at larval stage L2 (PubMed:24885717). {ECO:0000269|PubMed:15102704, ECO:0000269|PubMed:15892873, ECO:0000269|PubMed:24885717}. |