| 176450 | Q22292 | TBX8_CAEEL | T-box transcription factor tbx-8 | DISRUPTION PHENOTYPE | RNAi-mediated knockdown causes about 5% embryonic lethality with 1-10% of hatching larvae displaying posterior morphological defects (PubMed:15102704, PubMed:15892873). Defective intercalation of dorsal hypodermis (PubMed:15102704). Simultaneous RNAi-mediated knockdown of tbx-9 causes at least 48% of embryos to fail to hatch and those that do display severe morphological defects and die as larvae (PubMed:15892873, PubMed:15102704). Simultaneous RNAi-mediated knockdown of tbx-9 abolishes muscle expression of vab-7 (PubMed:15102704). {ECO:0000269|PubMed:15102704, ECO:0000269|PubMed:15892873}. |