| 176526 | G5ECN5 | STRD1_CAEEL | STE20-related kinase adapter protein strd-1 (STRAD STE20-related adapter homolog) | DISRUPTION PHENOTYPE | Ectopic expression of pre-synaptic reporter snb-1-GFP in ASI sensory neurons. Along the dorsal nerve cord of DD motoneurons, pre-synaptic puncta appear diffuse or smaller and synapse localization of sad-1 is disrupted. Germline hyperplasia and loss of aak-2 phosphorylation during dauer development (PubMed:20110331). During neuroblast division, daughter cell size asymmetry in the Q.p division is defective (PubMed:23267054). Animals are slightly stiff but with active locomotion (PubMed:20023164). In par-4 (it33) mutants, causes embryonic lethality (PubMed:20023164). In ced-3 (n3692) mutants, impaired cell shedding during embryogenesis which results in the generation of an ectopic excretory cell (PubMed:22801495). In addition, these double mutants produce additional AVM or PVM mechanosensory neurons (PubMed:23267054). {ECO:0000269|PubMed:20023164, ECO:0000269|PubMed:20110331, ECO:0000269|PubMed:22801495, ECO:0000269|PubMed:23267054}. |