| 176625 | Q17345 | CNOT7_CAEEL | CCR4-NOT transcription complex subunit 7 (EC 3.1.13.4) (CCR4-associated factor 1) (CAF1) | DISRUPTION PHENOTYPE | RNAi-mediated knockdown either results in sterility or a reduced brood size (PubMed:23843623). RNAi-mediated knockdown disrupts the arrangement, differentiation and maturation of oocytes in the proximal region and as a result small oocyte-like cells arrange in several rows in the germline (PubMed:23843623). RNAi-mediated knockdown reduces miRNA-mediated deadenylation (PubMed:28204614). RNAi-mediated knockdown reduces ccr-4 and ntl-1 protein levels (PubMed:28204614). In another study, RNAi-mediated knockdown does not alter the levels of let-711 or ccr-4 (PubMed:23843623). RNAi-mediated knockdown results in reduced global poly(A) tail deadenylation (PubMed:23843623). {ECO:0000269|PubMed:23843623, ECO:0000269|PubMed:28204614}. |