Mine Disruption Phenotype

Gene Info

  • Species:Worm (Caenorhabditis elegans)
  • GeneID:176939
  • Symbol:dsl-1
  • Description:Delta-like protein
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Gene ID Entry Entry Name Protein Name Type Information
176939 O45201 DSL1_CAEEL Delta-like protein dsl-1 (DSL-domain containing protein dsl-1) DISRUPTION PHENOTYPE Causes adjacent vulval precursor cells (VPCs) to adopt altered cell fate; phenotype exacerbated when combined with simultaneous RNAi-mediated knockdown of apx-1 and lag-2, and further worsened on lin-15 mutant background (PubMed:14960273). Severe vulval precursor cell (VPC) fate abnormalities, vulval defects and failure to up-regulate lip-1 expression, on an osm-11 mutant background (PubMed:18700817). {ECO:0000269|PubMed:14960273, ECO:0000269|PubMed:18700817}.