Mine Disruption Phenotype

Gene Info

  • Species:Worm (Caenorhabditis elegans)
  • GeneID:177157
  • Symbol:hlh-30
  • Description:BHLH domain-containing protein
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Gene ID Entry Entry Name Protein Name Type Information
177157 H2KZZ2 HLH30_CAEEL Helix-loop-helix protein 30 DISRUPTION PHENOTYPE RNAi-mediated knockdown in adults reduces lifespan on eat-2, daf-2 and rsks-1 mutant backgrounds (PubMed:23925298). RNAi-mediated knockdown during the fourth larval stage reduces lifespan on a clk-1 mutant background (PubMed:23925298). RNAi-mediated knockdown reduces the expression of mml-1 on a glp-1 mutant background (PubMed:27001890). RNAi-mediated knockdown increases expression of lmp-1 and sqst-1 (PubMed:23925298). {ECO:0000269|PubMed:23925298, ECO:0000269|PubMed:27001890}.