Gene ID | Entry | Entry Name | Protein Name | Type | Information | 177413 | Q17569 | DDI1_CAEEL | Protein DDI1 homolog 1 (EC 3.4.23.-) | DISRUPTION PHENOTYPE | Increased sensitivity to low doses of bortezomib which causes proteasome dysfunction. Double knockout with proteasomal subunit pbs-5 or with rpt-5 knockdown results in failed expression of the proteasomal subunit rpt-3. Double knockout with pbs-5 also results in the occasional mis-localization of the transcription factor skn-1a within gut nuclei. {ECO:0000269|PubMed:27528192}. |
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