Mine Disruption Phenotype

Gene Info

  • Species:Worm (Caenorhabditis elegans)
  • GeneID:177460
  • Symbol:jnk-1
  • Description:Stress-activated protein kinase jnk-1
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Gene ID Entry Entry Name Protein Name Type Information
177460 Q8WQG9 JNK1_CAEEL Stress-activated protein kinase jnk-1 (EC 2.7.11.24) DISRUPTION PHENOTYPE RNAi-mediated knockdown prevents Mn(2+)-induced dopaminergic CEP neuron degeneration (PubMed:23721876). RNAi-mediated knockdown targeted to neurons results in increased total time in sleep bouts (PubMed:29523076). {ECO:0000269|PubMed:23721876, ECO:0000269|PubMed:29523076}.