177486 | V6CLA2 | HECD1_CAEEL | E3 ubiquitin-protein ligase hecd-1 (EC 2.3.2.26) | DISRUPTION PHENOTYPE | RNAi-mediated knockdown causes no visible phenotype (PubMed:20153198). RNAi-mediated knockdown in a glp-1(ar202) mutant background causes an increase in the number of sterile animals (PubMed:25552605). RNAi-mediated knockdown in a vab-10(e698) mutant background causes 50 percent larval lethality associated with the detachment of muscles from the epidermis (PubMed:20153198). {ECO:0000269|PubMed:20153198, ECO:0000269|PubMed:25552605}. |