Mine Disruption Phenotype

Gene Info

  • Species:Worm (Caenorhabditis elegans)
  • GeneID:177486
  • Symbol:hecd-1
  • Description:E3 ubiquitin-protein ligase hecd-1;HECT-type E3 ubiquitin transferase
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Gene ID Entry Entry Name Protein Name Type Information
177486 V6CLA2 HECD1_CAEEL E3 ubiquitin-protein ligase hecd-1 (EC 2.3.2.26) DISRUPTION PHENOTYPE RNAi-mediated knockdown causes no visible phenotype (PubMed:20153198). RNAi-mediated knockdown in a glp-1(ar202) mutant background causes an increase in the number of sterile animals (PubMed:25552605). RNAi-mediated knockdown in a vab-10(e698) mutant background causes 50 percent larval lethality associated with the detachment of muscles from the epidermis (PubMed:20153198). {ECO:0000269|PubMed:20153198, ECO:0000269|PubMed:25552605}.