| 178135 | Q23551 | UNC22_CAEEL | Twitchin (EC 2.7.11.1) (Uncoordinated protein 22) | DISRUPTION PHENOTYPE | Body muscles are unable to develop or sustain normal contractions but small regions within the myofilament lattice of individual muscle cells contract transiently in the absence of contraction of the adjacent lattice (PubMed:16765996, PubMed:7190524). This results in a nearly constant body twitching phenotype (PubMed:16765996, PubMed:7190524, PubMed:25851606). Resistant to nicotine-induced paralysis (PubMed:25851606). {ECO:0000269|PubMed:16765996, ECO:0000269|PubMed:25851606, ECO:0000269|PubMed:7190524}. |