Mine Disruption Phenotype

Gene Info

  • Species:Worm (Caenorhabditis elegans)
  • GeneID:178855
  • Symbol:soc-1
  • Description:Multisubstrate adapter protein soc-1
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Gene ID Entry Entry Name Protein Name Type Information
178855 G5EDJ4 SOC1_CAEEL Multisubstrate adapter protein soc-1 (Suppressor Of Clr protein 1) DISRUPTION PHENOTYPE Causes a decrease in synaptic levels of lev-1, unc-38 and unc-49, a moderate resistance to paralysis induced by nicotine and levamisole (PubMed:15990870) and a mild increase in uncoordinated movements. In addition, forms ectopic muscle membrane extension during larval stage (PubMed:16495308). Rescues fluid accumulation in clr-1 e1745ts mutant (PubMed:11689700). Partially suppresses multi-vulva formation and partially restores fertility in let-60 1046gf mutant (PubMed:16547100). Prevents constitutive dauer formation in daf-2 m577 mutant (PubMed:16547100). {ECO:0000269|PubMed:11689700, ECO:0000269|PubMed:15990870, ECO:0000269|PubMed:16495308, ECO:0000269|PubMed:16547100}.