Mine Disruption Phenotype

Gene Info

  • Species:Worm (Caenorhabditis elegans)
  • GeneID:179192
  • Symbol:spr-1
  • Description:REST corepressor spr-1
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Gene ID Entry Entry Name Protein Name Type Information
179192 Q18919 RCORB_CAEEL REST corepressor spr-1 (CoREST) (Suppressor of presenilin 1) DISRUPTION PHENOTYPE Loss of function results in a suppression of sel-12 mutant phenotypes, possibly by up-regulating hop-1 expression (PubMed:12411496). Double knockout with lin-35 results in defects in growth, vulval morphogenesis, somatic gonad development and fertility (PubMed:17070797). {ECO:0000269|PubMed:12411496, ECO:0000269|PubMed:17070797}.