Mine Disruption Phenotype

Gene Info

  • Species:Worm (Caenorhabditis elegans)
  • GeneID:179475
  • Symbol:mics-1
  • Description:Mitochondrial scaffolding protein 1;PDZ domain-containing protein
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Gene ID Entry Entry Name Protein Name Type Information
179475 Q22638 MICS1_CAEEL Mitochondrial scaffolding protein 1 DISRUPTION PHENOTYPE RNAi-mediated knockdown in young adults results in an increased adult lifespan. At 37 degrees Celsius, levels of reactive oxygen species are reduced compared to wild-type animals. Double knockout with atad-3 RNAi results in an enhanced increase in adult lifespan as compared to the single mutants and wild-type animals. {ECO:0000269|PubMed:22245785}.