| 179527 | G5EFU0 | PK2_CAEEL | Serine/threonine-protein kinase pak-2 (EC 2.7.11.1) (p21-activated kinase 2) | DISRUPTION PHENOTYPE | Low level of embryonic lethality (< 15 percent) which is suppressed by simultaneous RNAi-mediated knockdown of max-2 (PubMed:19797046). In pak-1 and pak-2 double mutants, defects in embryogenesis and L1 stage lethality. The few animals reaching adulthood are smaller but have normal ventral cord commissural motoneuron axonal guidance and are relatively coordinated (PubMed:17050621, PubMed:19797046). {ECO:0000269|PubMed:17050621, ECO:0000269|PubMed:19797046}. |