Mine Disruption Phenotype

Gene Info

  • Species:Worm (Caenorhabditis elegans)
  • GeneID:179649
  • Symbol:pkc-1
  • Description:Protein kinase C;Protein kinase C-like 1B
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Gene ID Entry Entry Name Protein Name Type Information
179649 P34885 KPC1B_CAEEL Protein kinase C-like 1B (PKC1B) (EC 2.7.11.13) DISRUPTION PHENOTYPE Attenuated response to nose touch stimulation. Defects in salt attraction. Disrupted chemotaxis. Hyperactivation of AFD thermosensory neurons but inactivation of the ASH neurons. Reduced dauer formation. Protection from hemiasterlin toxicity by carbonyl cyanide p-[trifluoromethoxy]-phenyl-hydrazone (FCCP) greatly reduced. Reduced neuropeptide secretion. {ECO:0000269|PubMed:15920475, ECO:0000269|PubMed:17128266, ECO:0000269|PubMed:20089839, ECO:0000269|PubMed:20837997, ECO:0000269|PubMed:21143768}.