179676 | P12844 | MYO3_CAEEL | Myosin-3 (Myosin heavy chain A) (MHC A) | DISRUPTION PHENOTYPE | Worms exhibit retarded embryonic development and paralysis (PubMed:2583106). Muscle organization shows disruption with abnormalities of both the filament lattice that constitutes the A-band and the hypodermal cell (PubMed:2583106). RNAi-mediated knockdown causes an accumulation in the proximal gonad of endomitotic mature oocytes in 51 percent of animals (PubMed:17326220). {ECO:0000269|PubMed:2583106, ECO:0000269|PubMed:3320053}. |