Mine Disruption Phenotype

Gene Info

  • Species:Worm (Caenorhabditis elegans)
  • GeneID:179676
  • Symbol:myo-3
  • Description:Myosin-3
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Gene ID Entry Entry Name Protein Name Type Information
179676 P12844 MYO3_CAEEL Myosin-3 (Myosin heavy chain A) (MHC A) DISRUPTION PHENOTYPE Worms exhibit retarded embryonic development and paralysis (PubMed:2583106). Muscle organization shows disruption with abnormalities of both the filament lattice that constitutes the A-band and the hypodermal cell (PubMed:2583106). RNAi-mediated knockdown causes an accumulation in the proximal gonad of endomitotic mature oocytes in 51 percent of animals (PubMed:17326220). {ECO:0000269|PubMed:2583106, ECO:0000269|PubMed:3320053}.