Mine Disruption Phenotype

Gene Info

  • Species:Worm (Caenorhabditis elegans)
  • GeneID:179959
  • Symbol:hda-1
  • Description:Histone deacetylase 1
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Gene ID Entry Entry Name Protein Name Type Information
179959 O17695 HDA1_CAEEL Histone deacetylase 1 (EC 3.5.1.98) DISRUPTION PHENOTYPE RNAi-mediated knockdown results in embryonic lethality. RNAi-mediated knockdown results in delayed cell cycle progression (PubMed:25446273). RNAi-mediated knockdown inhibits expression of hsp-6 when adults are exposed to conditions causing mitochondrial stress (PubMed:32934238). Reduces the dve-1 protein level (PubMed:32934238). {ECO:0000269|PubMed:25446273, ECO:0000269|PubMed:32934238, ECO:0000269|PubMed:9875852}.