| 180982 | Q18825 | BAR1_CAEEL | Beta-catenin/armadillo-related protein 1 (Protruding vulva protein 1) (Suppressor of polyray 1) | DISRUPTION PHENOTYPE | Abnormalities in vulval development due to incorrect cell fate specification, resulting in the following phenotypes, multivulva (Muv), protruding vulva (Pvl) and egg laying defective (Egl) (PubMed:9716532, PubMed:11063687, PubMed:11560894, PubMed:12441291). Mutants also show defects in Q neuroblast migration, uncoordinated movement (Unc) and reduced superoxidase dismutase levels (PubMed:15905404). Mutants can be rescued by wrm-1 and hmp-2 when expressed from the bar-1 promoter (PubMed:11560894). Double knockout with dpy-22 result in reduced body length, male tail morphology abnormalities (Mab) and dauer induction (PubMed:12441291). RNAi-mediated knockdown in the intestine decreases E.faecium-mediated protection against S.enterica infection (PubMed:35263319). {ECO:0000269|PubMed:11063687, ECO:0000269|PubMed:11560894, ECO:0000269|PubMed:12441291, ECO:0000269|PubMed:15905404, ECO:0000269|PubMed:35263319, ECO:0000269|PubMed:9716532}. |