Mine Disruption Phenotype

Gene Info

  • Species:Worm (Caenorhabditis elegans)
  • GeneID:181124
  • Symbol:unc-27
  • Description:Troponin I 2
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Gene ID Entry Entry Name Protein Name Type Information
181124 Q9GYF1 TNNI2_CAEEL Troponin I 2 (CeTNI-2) (TnI 2) (Uncoordinated protein 27) DISRUPTION PHENOTYPE Worms exhibit abnormal locomotion, unregulated contraction of the sarcomeres due to small portions of each myofibril shortening irregularly and independently from another causing rigid paralysis. This is due to poorly defined sarcomeric structure, with small islands of thin filaments interspersed within the overlap region of A bands and the H zone. {ECO:0000269|PubMed:14747334}.