| 181271 | Q7JM44 | SMA9_CAEEL | Transcription factor sma-9 | DISRUPTION PHENOTYPE | RNAi-mediated knockdown causes a reduction in acetylcholine (ACh) content, altered sensitivity to Aldicarb, a potent acetylcholinesterase (AChE) inhibitor, reduced expression of vesicular acetylcholine transporter unc-17 and elevated levels of reactive oxygen species (PubMed:25407930). Knockdown inhibits nuclear localization of transcription factor daf-16 (PubMed:25407930). In response to nano-polystyrene, causes decreased locomotion behavior and increased reactive oxygen species (ROS) production (PubMed:20687916). Intestine-specific RNAi-mediated knockdown causes increased ROS production and reduces expression of elt-2 and hsp-6 (PubMed:20687916). Represses the mitochondrial unfolded protein response (mtUPR) induced by exposure to nano-polystyrene (PubMed:20687916). {ECO:0000269|PubMed:20687916, ECO:0000269|PubMed:25407930}. |