Mine Disruption Phenotype

Gene Info

  • Species:Worm (Caenorhabditis elegans)
  • GeneID:181371
  • Symbol:set-6
  • Description:SET domain-containing protein
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Gene ID Entry Entry Name Protein Name Type Information
181371 O17679 SET6_CAEEL Histone-lysine N-methyltransferase set-6 (EC 2.1.1.-) (EC 2.1.1.366) DISRUPTION PHENOTYPE RNAi-mediated knockdown prevents age-related decline in the expression of bas-1, a serotonin (5-HT) and dopamine synthesizing enzyme (DOPA decarboxylase) (PubMed:32103178). RNAi-mediated knockdown improves behavioral performance in pharyngeal pumping in aged worms (PubMed:32103178). {ECO:0000269|PubMed:32103178}.