Mine Disruption Phenotype

Gene Info

  • Species:Worm (Caenorhabditis elegans)
  • GeneID:181697
  • Symbol:sgk-1
  • Description:Serine/threonine-protein kinase sgk-1
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Gene ID Entry Entry Name Protein Name Type Information
181697 Q2PJ68 SGK1_CAEEL Serine/threonine-protein kinase sgk-1 (EC 2.7.11.1) (Serum- and glucocorticoid-inducible kinase homolog) (Serum/glucocorticoid-regulated kinase 1) DISRUPTION PHENOTYPE A mild developmental delay, extended generation time, an extension of life span, defective egg-laying and decreased body size, but increased lipid storage (PubMed:15068796, PubMed:18782349, PubMed:19240135, PubMed:19260765). RNAi-mediated knockdown abolishes expression of the vitellogenin vit-3 (PubMed:27401555). {ECO:0000269|PubMed:15068796, ECO:0000269|PubMed:18782349, ECO:0000269|PubMed:19240135, ECO:0000269|PubMed:19260765, ECO:0000269|PubMed:27401555}.