Mine Disruption Phenotype

Gene Info

  • Species:Worm (Caenorhabditis elegans)
  • GeneID:187442
  • Symbol:dyf-5
  • Description:Serine/threonine-protein kinase dyf-5
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Gene ID Entry Entry Name Protein Name Type Information
187442 B3WFY8 DYF5_CAEEL Serine/threonine-protein kinase dyf-5 (EC 2.7.11.1) DISRUPTION PHENOTYPE Sensory neuron cilia are longer, not correctly aligned in the amphid channel, more dispersed, misdirected and sometimes turned back towards the transition zone. Abnormal localization of kap-1 along the full cilia length. Abnormal accumulation in the middle of cilia and in the distal segment and reduced speed along the cilium axoneme of components of the IFT machinery kap-1, osm-3, xbx-1, che-11 and osm-5. In a kap-1 mutant background, 30 percent of mutants have branched cilia. In a kap-1 and osm-3 double mutant background, loss of cilia formation. {ECO:0000269|PubMed:17420466}.