| 189783 | Q9XW26 | SPTF3_CAEEL | Specificity protein transcription factor 3 | DISRUPTION PHENOTYPE | RNAi-mediated knockdown causes defects in cell fate, embryonic morphogenesis, and embryonic and larval lethality (PubMed:21884786, PubMed:23851392). Defects in gastrulation; failure of endodermal E cells to internalize at the 26- to 28-cell stage (PubMed:26434722). Reduces cell cycle lengths significantly in endodermal E cells (PubMed:26434722). Significant reduction in expression of end-1 and end-3, and enhances the disruption of intestinal development in an end-3 mutant background (PubMed:26434722). Reduces number of offspring, and the production of oocytes is compromised (PubMed:21884786). Failure of cell death in pharyngeal M4 motor neuron sister (PubMed:21884786). {ECO:0000269|PubMed:21884786, ECO:0000269|PubMed:23851392, ECO:0000269|PubMed:26434722}. |