| 191619 | G5EE18 | CEH28_CAEEL | Homeobox protein ceh-28 (NK-2 homeodomain factor CEH-28) | DISRUPTION PHENOTYPE | Reduced pharynx pumping rate and abnormal isthmus peristalses in L1 stage larvae (PubMed:18161854). Feeding defects, characterized by a stuffed pharynx, as a result of ingested E.coli packing the lumen of the corpus and anterior isthmus in L4 stage larvae (PubMed:18161854). Defects in pharyngeal g1 gland cell morphology (PubMed:24690231). Reduced expression of TGF-beta, dbl-1, in the cholinergic motor neuron M4, but normal expression of other markers of differentiation, such as serotonin receptor ser-7b and the vesicular acetylcholine transporter unc-17 (PubMed:18161854). {ECO:0000269|PubMed:18161854, ECO:0000269|PubMed:24690231}. |