Mine Disruption Phenotype

Gene Info

  • Species:Worm (Caenorhabditis elegans)
  • GeneID:259448
  • Symbol:oig-4
  • Description:Immunoglobulin domain-containing protein oig-4
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Gene ID Entry Entry Name Protein Name Type Information
259448 Q5WRU0 OIG4_CAEEL Immunoglobulin domain-containing protein oig-4 DISRUPTION PHENOTYPE Disrupted localization of levamisole-sensitive nicotinic acetylcholine receptor subunits in 80% of mutants, and this is mostly in conjunction with the disrupted localization of the associated transmembrane protein lev-10 and secreted protein lev-9. This results in increased sensitivity to the acetylcholine agonist levamisole. {ECO:0000269|PubMed:21252855}.