| Gene ID | Entry | Entry Name | Protein Name | Type | Information | 266847 | O17966 | TOP1_CAEEL | DNA topoisomerase 1 (EC 5.6.2.1) (DNA topoisomerase I) (topoI) | DISRUPTION PHENOTYPE | RNAi-mediated knockdown causes abnormal gonad morphology, enlarged sperm nuclei and aberrant progression through meiosis. Oocytes appear to have undergone endomitotic reduplication. {ECO:0000269|PubMed:16943775}. |
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