Mine Disruption Phenotype

Gene Info

  • Species:Worm (Caenorhabditis elegans)
  • GeneID:3565407
  • Symbol:kin-1
  • Description:cAMP-dependent protein kinase;cAMP-dependent protein kinase catalytic subunit
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Gene ID Entry Entry Name Protein Name Type Information
3565407 P21137 KAPC1_CAEEL cAMP-dependent protein kinase catalytic subunit (PKA C) (EC 2.7.11.11) DISRUPTION PHENOTYPE RNAi-mediated knockdown of isoforms a and b in neurons shows a temperature-sensitive adult onset paralysis of the distal part of the body resulting in the loss of backward movements and an inability to lay eggs. RNAi-mediated knockdown of isoforms f and k results in no obvious phenotype. {ECO:0000269|PubMed:18077108}.