Mine Disruption Phenotype

Gene Info

  • Species:Fly (Drosophila melanogaster)
  • GeneID:31310
  • Symbol:Myc
  • Description:Myc
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Gene ID Entry Entry Name Protein Name Type Information
31310 Q9W4S7 MYC_DROME Myc protein (Diminutive protein) (dMyc1) DISRUPTION PHENOTYPE RNAi-mediated knockdown in the neurons, only dopaminergic neurons or only adult neurons increases transcription of the dopamine decarboxylase Ddc and thereby dopamine concentration (PubMed:35167135). In addition, induces male courtship propensity towards other males without altering male sexual preference towards females (PubMed:35167135). RNAi-mediated knockdown in muscle or fat body does not elicit male-male courtship (PubMed:35167135). Simultaneous knockdown of Ddc and myc restores increased dopamine levels and the induced male-male courtship observed in the single myc knockdown (PubMed:35167135). Simultaneous knockdown of dopamine receptor Dop1R1 and myc restores the induced male-male courtship observed in the single myc knockdown (PubMed:35167135). {ECO:0000269|PubMed:35167135}.