Mine Disruption Phenotype

Gene Info

  • Species:Fly (Drosophila melanogaster)
  • GeneID:32608
  • Symbol:mei-41
  • Description:meiotic 41
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Gene ID Entry Entry Name Protein Name Type Information
32608 Q9VXG8 ATR_DROME Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein homolog) (ATR homolog) (dATR) (Meiotic protein 41) DISRUPTION PHENOTYPE In embryos, during S phase of mid-blastula transition, fails to delay the activation of Cdk1, leads to loss of Rif1 foci, and results in cells entering prematurely into mitosis 13 before the completion of replication resulting in chromosome bridging. {ECO:0000269|PubMed:29746464}.