| 32690 | Q9VX88 | WAC_DROME | WW domain-containing adapter protein with coiled-coil homolog (Protein wacky) | DISRUPTION PHENOTYPE | Neurodegeneration, slow growth, decreased starvation-induced autophagy, increased basal autophagy and decreased Tor activity (PubMed:26812014). RNAi-mediated knockdown in neurons results in impaired habituation during a light-off jump reflex habituation assay where flies are exposed to a series of sudden light-off pulses and measured each time for a jump response (PubMed:26757981). Mutants fail to adapt their behavior and retain high average jump response throughout the experiment in contrast to controls which quickly habituate to the repeated light-off stimuli (PubMed:26757981). {ECO:0000269|PubMed:26757981, ECO:0000269|PubMed:26812014}. |