| 33001 | Q9VWB9 | THADA_DROME | Thyroid adenoma-associated protein homolog | DISRUPTION PHENOTYPE | No visible phenotype. However, flies are hypersensitive to the cold, hyperphagic and display elevated triglyceride stores resulting in an increased resistance to starvation. Heat production is impaired and flies are slow to recover after cold treatment. The size of the lipid droplets in larval fat bodies are significantly increased and flies display increased feeding. Total body glycogen is also significantly increased in adult females but not in males. Mutants also display an increase in calcium-dependent SERCA activity. No effect on levels of circulating sugars, glucose and trehalose. {ECO:0000269|PubMed:28399403}. |