Mine Disruption Phenotype

Gene Info

  • Species:Fly (Drosophila melanogaster)
  • GeneID:33196
  • Symbol:smo
  • Description:smoothened
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Gene ID Entry Entry Name Protein Name Type Information
33196 P91682 SMO_DROME Protein smoothened (dSMO) (SMOH) (Smooth) DISRUPTION PHENOTYPE RNAi-mediated knockdown severely reduces adult survival following the ingestion of E.carotovora. Abolishes Cad99C-dependent formation of endosomes and DUOX-dependent up-regulation of reactive oxygen species (ROS) in the intestines of adults fed bacteria-derived uracil. {ECO:0000269|PubMed:25639794}.