| 33659 | Q9VR07 | INE_DROME | Sodium- and chloride-dependent GABA transporter ine (Protein inebriated) (Protein receptor oscillation A) | DISRUPTION PHENOTYPE | Flies lacking this protein, in a wild-type background, display no observable behavioral defects. In a Shaker mutant background, flies lacking ine exhibit downturned wings and an indented thorax. Flies lacking ine exhibit increased excitability of the larval peripheral nerve by causing the defective re-uptake of the substrate neurotransmitter of the ine transporter and thus overstimulation by this neurotransmitter. Flies lacking ine increase the growth of the perineurial glial layer of the larval peripheral nerve. Flies overexpressing ine exhibit delayed onset of long-term facilitation and increased failure rate of transmitter release at the larval neuromuscular junction, reduced amplitude of larval nerve compound action potentials, suppression of the leg-shaking behavior of mutants defective in the Shaker-encoded potassium channel, and temperature-sensitive paralysis. {ECO:0000269|PubMed:1334137}. |