| 34364 | P23128 | DDX6_DROME | ATP-dependent RNA helicase me31b (EC 3.6.4.13) (Maternal expression at 31B) | DISRUPTION PHENOTYPE | Larvae lethal at the second- or third-instar stage (PubMed:11546740). RNAi-mediated knockdown in adult pigment dispersing factor (Pdf)-expressing clock neurons results in poor circadian locomotor rhythms under constant dark (DD) conditions (PubMed:28388438). The axonal terminus of s-LNv neurons display a loss of Pdf circadian daily oscillations which is consistent with their behavioral arrhythmicity (PubMed:28388438). However, there is no effect on the daily oscillations of pir and tim proteins in Pdf neurons (PubMed:28388438). Double knockdown with Atx2 enhances the behavioral arrhythmicity (PubMed:28388438). RNAi-mediated knockdown in the dorsal-most class IV neurons frequently results in defects in terminal dendrite morphology and dendritic tiling (PubMed:17178403). RNAi-mediated knockdown in adult projection neurons increases levels of the translational reporter protein CaMKII in the antennal lobe (PubMed:21267420). RNAi-mediated knockdown in the anterior/posterior boundary of the wing imaginal disk causes loss of DCP1- and pcm-expressing P-bodies (PubMed:17982591). {ECO:0000269|PubMed:11546740, ECO:0000269|PubMed:17178403, ECO:0000269|PubMed:17982591, ECO:0000269|PubMed:21267420, ECO:0000269|PubMed:28388438}. |