| 34445 | Q23978 | MY31D_DROME | Unconventional myosin ID (MyoID) (Brush border myosin IA) (BBMIA) (Myosin 1D) (Myo1D) (Myosin-IA) (MIA) (MyoIA) | DISRUPTION PHENOTYPE | Viable and fertile (PubMed:16598258). Mutant embryos and adults display normal foregut left-right asymmetry, but inverted left-right asymmetry of the midgut and hindgut (PubMed:16598258, PubMed:18521948). RNAi-mediated knockdown in the hindgut at 0 to 24 hours after pupation leads to inverted left-right asymmetry of the adult hindgut, but knockdown at later stages has little or no effect (PubMed:16598258, PubMed:26073018). Adults display inverted left-right asymmetry of the male genitalia (PubMed:16598258). RNAi-mediated knockdown in the anterior and the posterior part of segment A8 of the male genital disk causes loss of the normal dextral rotation of the genital plate and inverted, sinistral spermiduct looping (PubMed:16598259, PubMed:26073018). Selective RNAi-mediated down-regulation in the anterior part of segment A8 of the male genital disk leads to partial dextral rotation of the genitalia, while RNAi-mediated down-regulation in the posterior part of segment A8 leads to non-rotated genitalia (PubMed:16598259). Combined RNAi-mediated knockdown of both ds and Myo31DF in the H1 segment of the imaginal ring causes mislooping of the adult hindgut (PubMed:26073018). {ECO:0000269|PubMed:16598258, ECO:0000269|PubMed:16598259, ECO:0000269|PubMed:18521948, ECO:0000269|PubMed:26073018}. |