Mine Disruption Phenotype

Gene Info

  • Species:Fly (Drosophila melanogaster)
  • GeneID:34453
  • Symbol:Trim9
  • Description:Tripartite motif containing 9
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Gene ID Entry Entry Name Protein Name Type Information
34453 M9MRI4 TRIM9_DROME E3 ubiquitin-protein ligase TRIM9 (EC 2.3.2.27) (Anomalies in sensory axon patterning protein) (asap) (RING-type E3 ubiquitin transferase TRIM9) (Tripartite motif containing protein 9) DISRUPTION PHENOTYPE Defective axonal patterning of terminal processes in class IV nociceptive sensory neurons (C4da), including defective contralateral projections in ddaC and vdaB neurons, during larval development (PubMed:22084112, PubMed:21338947, PubMed:24746793). Defective larval locomotion behavior (PubMed:22084112). Defective targeting of R8 photoreceptor growth cones to the medulla layer during eye development (PubMed:27743477). {ECO:0000269|PubMed:21338947, ECO:0000269|PubMed:22084112, ECO:0000269|PubMed:24746793, ECO:0000269|PubMed:27743477}.