| 34882 | Q9V3Z6 | MYO7A_DROME | Myosin-VIIa (DmVIIa) (Protein crinkled) | DISRUPTION PHENOTYPE | Flies exhibit altered morphology of setae, micro- and macrochaetae on the head, thorax and wing (PubMed:15579689). The number and distribution of setae on the thorax is altered, as is the morphology of the aristae (PubMed:15579689). Mutants also exhibit scolopidial apical detachment and overall Johnston's organ (JO) disorganization (PubMed:15579689). RNAi-mediated knockdown in Johnston's organs, disrupts the filamentous structure of the glycoprotein NompA at the apical junction (PubMed:27331610). NompA occurs as puncta and scolopidia detatch from the hinge of the second and third antennal segment (PubMed:27331610). {ECO:0000269|PubMed:15579689, ECO:0000269|PubMed:27331610}. |