Mine Disruption Phenotype

Gene Info

  • Species:Fly (Drosophila melanogaster)
  • GeneID:35524
  • Symbol:Src42A
  • Description:Src oncogene at 42A
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Gene ID Entry Entry Name Protein Name Type Information
35524 Q9V9J3 SRC42_DROME Tyrosine-protein kinase Src42A (EC 2.7.10.2) (Tyrosine-protein kinase Src41) (Dsrc41) DISRUPTION PHENOTYPE Following epithelial wounding, no migration of macrophages to wound sites (PubMed:26028435). RNAi-mediated knockdown in glial cells potently suppresses glial phagocytic activity with drpr not recruited to severed maxillary palp axons, blockage of glial hypertrophy, blockage of drpr up-regulation after antennal ablation and reduced clearance of severed axons in the central nervous system (PubMed:18432193). {ECO:0000269|PubMed:18432193, ECO:0000269|PubMed:26028435}.