Mine Disruption Phenotype

Gene Info

  • Species:Fly (Drosophila melanogaster)
  • GeneID:36876
  • Symbol:unc-104
  • Description:uncoordinated-104
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Gene ID Entry Entry Name Protein Name Type Information
36876 A1ZAJ2 KIF1A_DROME Kinesin-like protein unc-104 (Protein immaculate connections) (DUnc104) DISRUPTION PHENOTYPE Flies prevent nerve endings from transforming to synaptic boutons: growth cones become constricted but remain within contact fields as thin processes that lack varicosities or boutons. Mutant embryos die at late stage, they are paralyzed and lacked the coordinated muscle peristalsis required for hatching. {ECO:0000269|PubMed:17643120}.