Mine Disruption Phenotype

Gene Info

  • Species:Fly (Drosophila melanogaster)
  • GeneID:38357
  • Symbol:FMRFaR
  • Description:FMRFamide Receptor
Export (tab separated) Export to Excel
Gene ID Entry Entry Name Protein Name Type Information
38357 Q9VZW5 FMAR_DROME FMRFamide receptor (DFR) (DrmFMRFa-R) DISRUPTION PHENOTYPE Deficits in simulated flight behavior with fewer or shorter duration of wing beats in tethered flies (PubMed:30110323). Dopaminergic neuron-specific knockout leads to shorter flight duration (PubMed:30110323). RNAi-mediated knockdown, either in adults or during pupal development, results in similar deficits in simulated flight behavior, whereas knockdown during larval development has no effect on flight behavior in the adult (PubMed:30110323). Pan-neuronal or dopaminergic neuron-specific RNAi-mediated knockdown leads to significantly shorter flight bouts (PubMed:30110323). {ECO:0000269|PubMed:30110323}.