Mine Disruption Phenotype

Gene Info

  • Species:Fly (Drosophila melanogaster)
  • GeneID:40030
  • Symbol:not
  • Description:non-stop
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Gene ID Entry Entry Name Protein Name Type Information
40030 Q9VVR1 NOT_DROME Ubiquitin carboxyl-terminal hydrolase nonstop (EC 3.4.19.12) (Deubiquitinating enzyme nonstop) (Ubiquitin thioesterase nonstop) (Ubiquitin-specific-processing protease nonstop) DISRUPTION PHENOTYPE Defects in the number and migration of glial cells located within the lamina plexus of the developing eye; the lack of glial cells causing mistargeting of the R1-R6 axons in the optic lobe. Lamina neuron development is normal. {ECO:0000269|PubMed:11182084, ECO:0000269|PubMed:18188155}.