| 40191 | Q9VW71 | FAT2_DROME | Fat-like cadherin-related tumor suppressor homolog (Protein kugelei) | DISRUPTION PHENOTYPE | Defects in actin filament orientation correlate with a failure of egg chambers to elongate during oogenesis (PubMed:19906848). In follicle cells, Rab10 protein polarizes normally along the apical-basal axis, but is mislocalized within the epithelial plane (PubMed:23369713). Epithelia migration is impaired and the structure of the basal membrane is disrupted (PubMed:23369713). {ECO:0000269|PubMed:19906848, ECO:0000269|PubMed:23369713}. |