| 40541 | A0A126GUP6 | MP1_DROME | Melanization protease 1 (EC 3.4.21.-) | DISRUPTION PHENOTYPE | RNAi-mediated knockdown is semi-pupal lethal, with 50% of pupae dying at the late pupal stage or during eclosion (PubMed:16861233). Adults display impaired melanization at the site of septic infection (septic injury) using either Gram-negative (E.coli) or Gram-positive bacteria (M.luteus) (PubMed:16861233). No significant increase in PPO1 activity after septic injury using fungi (B.bassiana) and bacteria (PubMed:16861233). Survival and induction of antimicrobial peptides (Dpt and Drs) is not affected after bacterial or fungal infection (PubMed:16861233). Aseptic wounding has no effect on survival (PubMed:22227521). {ECO:0000269|PubMed:16861233, ECO:0000269|PubMed:22227521}. |